Background& Objectives: Enteric fever is a global public health problem, and over 21 million are getting infected and 0.2 million people are died annually. Almost 90% of the cases were from Asia.3 The trend of enteric fever prevalence is increasing worldwide with emergence of antimicrobial resistance, especially the multidrug resistance to ampicillin, chloramphenicol and cotrimoxazole is a major public health problem which further complicates the treatment and management of enteric fever. Objectives: To study the antimicrobial susceptibility pattern of Enteric fever among children between 1 to 14 years. Methods: The present Descriptive observational study was carried out at Department of Paediatrics, VIMS, Bellary involving 100 children between 1-14 years, clinically diagnostic of enteric fever during the period from January 2020 to January 2021. Result: Out of these 100 children, majority i.e., 51% were from 6-10 years, mean age of the study population was 7.67±3.09 years. 45% were males and 55% were females in our study. Antibiotic susceptibility pattern of Enteric fever revealed resistance to Cotrimoxazole in 17% cases, Chloramphenicol in 16% cases and Amoxicillin in 12% cases. Antibiotic susceptibility pattern according to organism revealed that s. typhi sensitive to Cotrimoxazole in 14% cases, Chloramphenicol in 10% cases, Amoxicillin in 9% cases. Conclusion: S. typhi was found resistance to Cotrimoxazole in 17% cases, Chloramphenicol in 16% cases, Amoxicillin in 12% cases and to Cipro floxacillin in 7% cases and sensitive to Cotrimoxazole in 14% cases, Chloramphenicol in 10% cases, Amoxicillin in 9% cases and to Cipro floxacillin in 5% cases. S. Paratyphi resistance to Cotrimoxazole in 3% cases, Chloramphenicol in 3% cases, Amoxicillin in 3% cases and to Cipro floxacillin in 3% cases.