Background: Breast cancer is most frequently diagnosed cancer among women and leading cause of cancer death in females worldwide.. The present study was conducted to analyze axillary lymph node positivity after radiological and histopathological investigations also to evaluate statistical relationship between breast lump size and axillary lymph node positivity. Material and methods: The study was conducted at Guru Nanak Dev Hospital, attached to Govt. Medical College, Amritsar, who presented with malignant breast lumps in either breast were assessed for enlarged axillary lymph nodes after approval from Institutional Ethics Committee, Government Medical College, Amritsar and informed consent from patients to be enrolled in study. This was a study of 50 cases that meet the inclusion and exclusion criteria. Patients were evaluated at base line for breast lump which include lump size it fixity, tenderness, nipple discharge, thickening or puckering of the skin and axillary lymph node status. Results and observation: On radiological metastatic workup it was found that out of 50 cases, mets were present in 8 (16%) cases on X-ray chest, 13 (26%) cases on X-ray LS spine and USG whole abdomen was found to be normal in all 50 cases. Correlation between breast lump size and axillary lymph node positivity showed that lymph node positivity in lump sizes <2cm is 16.66% and lump size >2cm is 93.75 proving that lymph node metastasis is more common in larger tumor size. Conclusion: We found that tumour size is a significant predictor of axillary nodal status, which can be used to separate some patients from an unnecessary full axillary dissection.