Background:Usually appearing blue or dark purple, varicose veins are twisted, bulging, and swollen. The legs and feet are where they are most frequently found. The present study was conducted to evaluate efficacy of sclerotherapy in managing varicose veins. Materials & Methods:70 cases of varicose veins of both genders were selected. Sclerotherapy was administered to patients using 0.3–0.5% sodium tetradecyl sulphate. After the sclerosant was injected, an elastic compression bandage was put on. For the following three months, the patient was instructed to wear the compression bandage. Results: Out of 70 patients, 40 were males and 30 were females. Symptoms were pain in 47, pigmentation in 41, eczema in 32, limb edema in 17, ulcer in 15, lipodermatosclerosis in 8, and others (Telangiectasia) in 3 patients. Complications of sclerotherapy was pigmentation in 2, deep vein thrombosis in 4, thrombophlebitis in 11, bruising in 2, skin necrosis in 5 and recurrence in 2 patients. The difference was significant (P< 0.05). Conclusion: Sclerotherapy is a rapid, secure, and effective way to treat varicose veins in the lower legs. The procedure is particularly effective for varicosities that persist after surgery and for smaller varicosities that emerge early, which may help prevent the development of skin changes.