Background: Proximal humerus fractures are common orthopedic injuries, particularly in elderly patients. Locking plates have emerged as a preferred fixation method, offering stable fixation and promoting early mobilization. This study aims to evaluate the functional outcomes of proximal humerus fractures treated with locking plates and functional evaluation using the Constant Murley Score (CMS). Methods: The study utilized 60 cases of displaced proximal humerus fractures classified by Neer's system. All patients underwent open reduction and internal fixation with a (Proximal Humerus Internal Locking System)PHILOS plate. The Constant score assessed functional performance by evaluating three aspects: pain levels combined with motion range restriction and muscle strength and activities of daily life. Results: This study analyzed 60 cases of proximal humerus fractures. The highest incidence was in the 41-50 age group (40%), with males (65%) more affected. Road traffic accidents were the leading cause (60%). Two-part fractures were most common (50%), and the right humerus was more frequently involved (65%). Most patients (65%) reported to the hospital on the same day. Functional evaluation showed that 40% had excellent outcomes, while 90% achieved union by nine weeks. Complications included osteonecrosis and screw cut-out in isolated cases, but no additional surgeries were required. Conclusion: Locking plate fixation for proximal humerus fractures demonstrated favorable functional and radiological outcomes. Most patients (90%) achieved fracture union within nine weeks, with excellent to good shoulder function observed in 70% of cases. Two-part and three-part fractures had better functional recovery, while four-part fractures showed higher complication rates.