Background and Aim: Preemptive analgesia is an anti-nociceptive treatment that prevents establishment of altered processing of afferent input, which amplifies postoperative pain.Gabapentinoids are anti-convulsants with membrane stabilizing and anti-nociceptive effects. This study was designed to evaluate the role of preoperative single dose of Pregabalin for attenuating postoperative pain and analgesic consumption in patients undergoing laparoscopic abdominal surgeries. Material and Methods: This study was conducted in 100 ASA grade I, II patients in the age group of 18-60 years undergoing elective laparoscopic surgeries under general anaesthesia. Patients were randomized and divided into 2 groups of 50 patients each. Group A was given capsule Pregabalin 150 mg orally 1 hour before surgery. Group B was given tab B complex orally 1 hour before surgery. Postoperative pain intensity was measured by Visual analogue scale at 1,2,4,6,8,12 and 24 hours after the surgery. Intraoperative Hemodynamic Monitoring was done. Results: The timing of first rescue analgesic postoperatively in Pregabalin group was 350.40± 72.08min compared to placebo group which was 171.60± 68.58 min. Consumption of Tramadol in Pregabalin group was 116.48± 42.13 mg and in placebo group, it was 174.10 ± 44.99 mg. Conclusion: Oral pregabalin significantly decreases incidence of pain postoperatively. It also decreases total tramadol consumption in comparison to placebo group in laparoscopic abdominal surgeries.