Background: Acne vulgaris is a common dermatological condition affecting approximately 85% of adolescents and young adults worldwide. Post-acne scarring represents a significant complication that can persist long after active acne resolves. While the physical manifestations of these scars are well-documented, their psychosocial impact remains understudied, particularly in the Indian context. Objective: This study aimed to evaluate the impact of post-acne scarring on quality of life (QoL) among young adults in India and identify factors that influence this relationship. Methods: A cross-sectional study was conducted among 312 Indian young adults (aged 18-30 years) with post-acne scarring. Participants completed the Dermatology Life Quality Index (DLQI), Patient Health Questionnaire-9 (PHQ-9), and the Acne Scar Quality of Life (AcneScQoL) questionnaire. Scar severity was assessed using the Goodman and Baron Qualitative Grading System. Multivariate regression analysis was performed to identify factors associated with QoL impairment. Results: Post-acne scarring significantly impacted QoL across multiple domains with the highest impairment in social functioning and self-perception. Females reported greater QoL impairment than males (p<0.001). Scar severity, visibility (facial location), and duration correlated positively with QoL impairment. Higher educational and socioeconomic status were associated with greater psychological impact of scarring. Conclusion: Post-acne scarring has a substantial impact on the QoL of young adults in India, with effects extending beyond physical appearance to psychological well-being and social functioning. These findings highlight the need for comprehensive acne management strategies that address both prevention and treatment of scarring, as well as the associated psychosocial burden.