Background: The study aimed to compare intraoperative and postoperative morbidity between carbon dioxide (CO2) laser tonsillectomy and dissection tonsillectomy in patients undergoing surgery for chronic or recurrent tonsillitis.Materials and Methods: A randomized clinical trial was conducted on 140 patients requiring tonsillectomy, with participants randomly assigned to two groups: Group A (CO2 laser tonsillectomy, n=70) and Group B (dissection tonsillectomy, n=70). Intraoperative parameters, including blood loss and surgical duration, were recorded. Postoperative pain was assessed using the Visual Analog Scale (VAS) at 6, 12, 24, and 48 hours. Secondary outcomes such as postoperative bleeding, time to resume a normal diet, hospital stay duration, and wound healing at 7 and 14 days were evaluated. Results: CO2 laser tonsillectomy resulted in significantly lower blood loss (21.5 ± 5.2 mL vs. 58.3 ± 7.6 mL, p<0.001) and shorter surgical duration (18.7 ± 3.1 min vs. 25.2 ± 4.3 min, p<0.001) compared to dissection tonsillectomy. Postoperative pain scores were significantly lower in the laser group at all-time points (p<0.001). Although early (4.29% vs. 10.00%, p=0.197) and late bleeding (2.86% vs. 7.14%, p=0.270) were less frequent in the laser group, differences were not statistically significant. Patients undergoing laser tonsillectomy resumed a normal diet sooner (3.2 ± 0.8 vs. 5.6 ± 1.2 days, p<0.001) and had a shorter hospital stay (1.4 ± 0.5 vs. 2.3 ± 0.7 days, p<0.001). Wound healing at 7 days was significantly better in the laser group (85.71% vs. 72.86%, p=0.045), with comparable healing at 14 days (97.14% vs. 90.00%, p=0.092).Conclusion: CO2 laser tonsillectomy demonstrated superior outcomes compared to dissection tonsillectomy, with reduced intraoperative blood loss, shorter surgical duration, lower postoperative pain, and faster recovery. While postoperative bleeding rates were lower in the laser group, the differences were not statistically significant. Initial wound healing was better in the laser group at 7 days, though both techniques achieved similar outcomes at 14 days. These findings support CO2 laser tonsillectomy as a safer and more efficient surgical technique.