Aim: This prospective study aimed to evaluate postoperative recovery and pain management outcomes in patients undergoing minimally invasive surgery (MIS) versus open abdominal surgery. Materials and Methods: A total of 120 patients were enrolled and divided into two groups: 60 underwent MIS, and 60 underwent open surgery. Patients were assessed preoperatively for baseline characteristics, and postoperative recovery metrics including pain scores, time to first ambulation, hospital stay, complications, and return to normal activities were measured. Pain levels were assessed using a numerical rating scale (NRS) during the first 48 hours post-surgery. Follow-up assessments were made at 1 week, 1 month, and 3 months post-surgery. Results: The MIS group reported significantly lower pain scores at all postoperative time points (6, 12, 24, and 48 hours) compared to the open surgery group (p < 0.01). Additionally, patients in the MIS group had quicker recovery, with earlier ambulation (10.2 ± 3.4 hours vs. 14.7 ± 5.2 hours) and shorter hospital stays (3.4 ± 1.1 days vs. 6.2 ± 2.3 days). Complication rates were lower in the MIS group, with fewer surgical site infections (1.7% vs. 8.3%) and less bleeding (3.3% vs. 10.0%). At 1 and 3 months post-surgery, the MIS group also reported better quality of life and functionality. Conclusion: This study highlights the superior outcomes of minimally invasive surgery in terms of reduced pain, quicker recovery, fewer complications, and better long-term functional outcomes compared to open surgery. These findings suggest that MIS is a beneficial approach for abdominal surgeries, improving both short- and long-term patient recovery.