Background: The advent of Microspot Carbon dioxide laser (250microns) made laser an appropriate tool for excision of superficial lesions of vocal cords which were initially treated only by micro dissection. The constant search for minimally invasive micro laryngeal surgery with maximum intact function saw the introduction of radiofrequency assisted plasma ablation as a tool in benign lesions of the vocal cords. Our study intends to find out the difference in outcome of Benign lesions of larynx, treated by Radiofrequency assisted plasma ablation and Carbon dioxide Laser, the potential advantages and disadvantages of each procedure, and any difference in duration of surgery. Methods: Adult patients who were presenting to ENT OPD and suspected to have benign lesions of the larynx are subjected to Videostroboscopy and diagnosis is confirmed. The patients are randomly allocated to treatment with Radiofrequency assisted plasma ablation and Carbon dioxide laser. Pretreatment voice assessment was made using Voice Handicap Index-10 (subjective) and Maximum Phonation Time (MPT). Results: Though both the methods are similar in terms of outcome, Laser surgery has significantly longer surgical times, and recovery also takes slightly longer when compared to Coblation surgery. Conclusions: This study suggests that Radiofrequency assisted plasma ablation and Carbon dioxide Laser both are excellent treatment modalities for the surgical management of Benign Lesions of the Larynx in the hands of an experienced surgeon. There were no detectable differences in the outcome between the two methods and there were no complications in any of these methods.