INTRODUCTION: The human abdomen, a complex and vital region of the body, harbours numerous structures susceptible to various pathologies, including the development of masses. Among these, masses located in the right iliac fossa (RIF) present a particular clinical challenge due to their diverse etiologies and potential complications. AIMS & OBJECTIVES Investigating different illnesses that may manifest as a mass in the right iliac fossa.Monitoring the cases studied for ongoing management and complication detection. MATERIALS AND METHODS This is a study of 100 cases of mass in the right iliac fossa admitted to Mahatma Gandhi memorial hospital ,warangal during the period from August 2022 to April 2024 over a span of 20 months. RESULTS RIF mass predominantly originates from conditions affecting the appendix, primarily manifesting as appendicular mass and abscess. This is followed by cases of carcinoma of the cecum and ileocecal tuberculosis. DISCUSSION This is a study of 100 cases of mass in the right iliac fossa admitted to Mahatma Gandhi memorial hospital ,warangal during the period from August 2022 to April 2024 over a span of 20 months .CONCLUSION The highest occurrence of masses in the right iliac fossa was observed in patients in their 30s and 40s. The majority of our patients were from low socio-economic backgrounds.