Background: Every year, influenza is a leading cause of acute respiratory tract infections. A number of neurologic side effects, such as Reye syndrome, Guillian-Barré, transverse myelitis, encephalopathy, and seizures, have also been linked to influenza virus infection. The present study was conducted to assess influenza associated neurological complications in children. Materials & Methods: 90 children of both genders were selected. Rapid assay (immunoassay [IA] or direct fluorescent antibody testing [DFA]) or thorough viral culture were used to diagnose all cases with a positive result for influenza A or B virus. Results: Out of 90 patients, 50 were males and 40 were females. Out of 90 patients, aseptic meningitis was seen in 5, febrile seizure in 6, seizure with fever in 12, post-infectious encephalopathy in 5 and encephalopathy in 8 cases. The mean hospitalization was 10.2 days, influenza A was seen in 58, influenza B in 32, respiratory symptoms were cough in 51 and dyspnea in 27 cases. The difference was significant (P< 0.05). Conclusion: The most frequent neurologic side effect in influenza patients is seizures.