Background: Hepatitis A virus (HAV) and Hepatitis E virus (HEV) are major causes of acute viral hepatitis, particularly in developing countries where sanitation and hygiene remain significant public health challenges. HAV primarily affects children and is associated with asymptomatic or mild self-limiting illness, while HEV predominantly affects adults and can lead to severe complications, especially in pregnant women. Understanding the epidemiological trends and prevalence of these infections is crucial for implementing effective public health interventions. Aim: This study aims to evaluate the prevalence, demographic distribution, and clinical characteristics of HAV and HEV infections in patients presenting with symptoms of acute viral hepatitis. The study also seeks to identify risk factors associated with infection and assess the need for targeted prevention strategies. Methods: A total of 608 patients were tested for HAV, and 475 patients were tested for HEV using enzyme-linked immunosorbent assay (ELISA) for IgM antibodies. Data on patient demographics, clinical symptoms, and laboratory findings were collected and analyzed using SPSS version 23.0. Statistical comparisons were performed to determine significant correlations between infection status and various demographic and clinical parameters. Results: The predominance of HAV was found to be 42.3% (257/608), with the highest infection rate observed in the pediatric population, particularly among children aged 5 years. In contrast, HEV infection was detected in only 0.2% (1/475) of the tested individuals, indicating a much lower burden in the study population. Male patients had a slightly higher prevalence of both HAV (55.0%) and HEV (54.1%), though the difference was not statistically significant. The most common symptoms in HAV-positive patients were jaundice (74%), fever (66%), and fatigue (58%). Due to the limited number of HEV cases, statistical comparisons for this virus were not feasible. Conclusion: HAV remains a significant public health concern, particularly among children, whereas HEV infection appears to be rare in the study population. The findings emphasize the need for improved sanitation, hygiene education, and the potential incorporation of hepatitis A vaccination into routine immunization programs. Recommendations: Improving hygiene, sanitation, and clean water access can reduce HAV and HEV transmission. Hepatitis A vaccination should be considered for children, and HEV surveillance strengthened to protect high-risk groups. Further research is needed to guide effective interventions.