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Volume 14 Issue 2 (February) 2025

Original Articles

Study of Clinical Profile of Anaemia in Patients with Inflammatory Bowel Disease
Dr. Arun Patted, Dr. Manjunath T. Shepur, Dr. Sharathchandra Khanappanavar, Dr.Preetham Hurkadli

Background: Anaemia is a common extra-intestinal manifestation of IBD (Inflammatory Bowel Disease), significantly impacting patients' quality of life. This study aims to evaluate the clinical profile and haematological parameters of anaemia in patients with IBD, focusing on CD (Crohn'sDisease) and UC (Ulcerative Colitis). Methods: A prospective observational study was conducted at a tertiary care hospital from November 2019 to December 2021. Patients diagnosed with IBD and haemoglobin levels below gender-specific cut-offs (men: <13 g/dL, women: <12 g/dL) were included. Data on demographic, clinical, and laboratory parameters were collected using structured case report forms. Results: The study included 100 patients (54% male, 46% female), with 69% diagnosed with Crohn's disease and 31% with ulcerative colitis. The majority (75%) were under 50 years old. The most common symptoms were abdominal pain (63%), fatigue (42%), and rectal bleeding (20%). Iron deficiency anaemia was predominant, with mean haemoglobin levels of 12.5 g/dL in CD and 12.3 g/dL in UC. Elevated CRP levels (mean: 17.7 mg/L) indicated active inflammation. Vitamin B12 deficiency was observed in 15% of patients, predominantly in CD. Conclusion: Anaemia in IBD is multifactorial, with iron deficiency being the most common cause. Regular haematological screening and early intervention are crucial for improving patient outcomes.

 
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