Objective:The research aimed to identify key occupational stressors contributing to sleep impairments and explore evidence-based interventions to mitigate their detrimental effects on individual well-being and workforce productivity. Methodology:A cross-sectional observational study was conducted utilizing a structured survey-based approach, encompassing 500 working professionals across diverse occupational sectors. The Perceived Stress Scale was employed to evaluate stress levels, while the Pittsburgh Sleep Quality Index served as a validated measure of sleep disturbances. Statistical analyses, including Pearson’s correlation, multiple regression modelling, and subgroup analyses, were performed to quantify the strength and significance of associations between stress, sleep quality, and contributing factors such as job strain, work hours, and lifestyle habits. Results:The findings unveiled a strong positive correlation (r = 0.68, p < 0.001) between occupational stress and sleep disturbances, demonstrating that individuals experiencing elevated stress levels reported significantly poorer sleep quality and reduced sleep duration. Participants classified under high stress conditions averaged only 5.4 hours of sleep, in stark contrast to 7.1 hours among those experiencing minimal stress. The prevalence of sleep impairments was disproportionately high among law enforcement (70.0%) and healthcare professionals (63.0%), underscoring the profound impact of high-pressure work environments on sleep health. Extended work hours exhibited a moderate correlation with sleep disturbances (r = 0.52, p = 0.002), while multiple regression analysis identified stress levels (β = 0.45, p < 0.001) as the most significant predictor of sleep disruption. Furthermore, lifestyle factors exerted a pivotal influence, with excessive caffeine consumption and prolonged screen exposure before bedtime exacerbating sleep disturbances, whereas regular physical activity and relaxation techniques served as protective factors, enhancing sleep quality and mitigating the deleterious effects of stress on sleep patterns. Conclusion:This study provided compelling empirical evidence that occupational stress is a critical determinant of sleep disturbances among working professionals, with job strain, excessive work hours, and high-pressure occupations exacerbating sleep impairments. The findings underscored the necessity for comprehensive workplace interventions, targeted stress management programs, and structured lifestyle modifications to mitigate the adverse impact of occupational stress on sleep health. Addressing these factors is not only paramount for individual health and psychological resilience but also imperative for fostering a more productive, sustainable, and high-functioning workforce. Future research should incorporate longitudinal methodologies and objective sleep assessments to further refine intervention strategies and establish causality in the stress-sleep nexus.