Background: Anemia is one of the most common diseases of pregnancy that includes inherited disorders and nutritional deficiency as the major causes of anemia. Pregnant females who have hemoglobinopathies and are asymptomatic before pregnancy can present with severe anemia in pregnancy owing to the physiological changes. Aim: The present study aimed to assess the feto-maternal outcomes along with neonatal and obstetric outcomes in pregnancies with hemoglobinopathy. Methods: The present study assessed 400 pregnant females with hemoglobinopathies where neonatal and maternal outcomes were assessed for the subjects that presented to the Institute within the defined study period. In all the included subjects, medical data were assessed and recorded followed by statistical analysis for formulation of the results. Results: Among 400 pregnant females with hemoglobinopathies, in different types of hemoglobinopathies, HbE homozygous has shown the highest presence with 39% (n=78) subjects. In obstetrics outcomes preterm were seen in 35.9% (n=28) subjects and cesarean deliveries in 60% (n=46) subjects, the highest maternal complications were seen in subjects with HbE with β Thalassemia trait with 87.2% (n=68) subjects. In the HbE homozygous group, NICU admissions and low birth weight were higher and seen in 54.1% (n=80) and 62.1% (n=92) study subjects respectively. Conclusion: The present study concludes that in subjects with feto-maternal complications, they are higher in subjects with HbE along with β Thalassemia trait, however, there is no associated neonatal stillbirth or maternal mortality in these subjects.