Split skin grafting (SSG) is commonly employed by surgeons for covering skin defects in case of ulcers, deep burns and following trauma. It is still the gold standard to cover large areas of skin loss4 and is relatively easy to perform. It involves harvesting of the epidermis and upper 1/3rd of dermis resulting in a wound called donor site wound (DSW). The cases are assessed according to the objectives like Rate of Epithelialisation, pain, pruritus, need of analgesia post-operatively. All the patients were explained about the basis of the study and informed consent is obtained. In our study of 70 patients, on post-operative day 7, 61(87.14%) patients showed spotty or scattered epithelialisation, out of which 26(74.29%) from group A & 35(100%) from group B, totally 9(12.86%) patients were infected or showed no epithelialisation, out of which all were from group A and none from group B. None of the patients from both groups show complete epithelialisation. ‘p’ value is significant in this group.