Background:Brown or grayish-brown spots that appear on the face, especially on the cheeks, forehead, nose, and upper lip, are a common sign of melasma, a skin disorder. The present study was conducted to compare 35% glycolic acid peel versus modified Kligman’s regimen in patients with Melasma.Materials & Methods: 50 patients with Melasma of both genders were selected. Random assignment was used to divide the patients into two groups of 25 each. For a total of twelve weeks, Group II underwent peels containing 35% glycolic acid once every four weeks, whereas Group I received topical modified Kligman's formula (MKF) daily.Results: Group I had 11 males and 14 females and group II had 10 males and 15 females. Common type was central in 12 and 11 and malar seen in 13 and 14 in group I and group II respectively. Disease duration was 1-2 years in 10 and 12, 2-3 years in 8 and 4 and >3 years in 7 and 9 patients in group I and group II respectively. The common precipitating factors were sun exposure in 11 and 7, cosmetics in 2 and 4, pregnancy in 9 and 10, drugs in 1 and 3, and idiopathic in 2 and 1 patient in group I and group II respectively. The difference was significant (P< 0.05). The pre-treatment mean MASI score in group I was 11.5 and in group II was 9.8 and post-treatment score was 3.7 in group I and 2.4 in group II. The difference was significant (P< 0.05).Conclusion: Glycolic acid peels and modified Kligman's recipe both worked well for melasma patients.