Background: LM or ligamentum mucosum has been implicated in plica syndrome which is a painful knee condition resulting from edematous, fibrotic, and thickened synovial plica. LM can be used for reconstruction of the anterior cruciate ligament tear. Aim: The present study was assessed for histological and Morphometric Evaluation of the Ligamentum Mucosum in Human Knee Joints. Methods: The study assessed 40 adult human cadavers. The intraarticular structures of the knee joint were exposed by reflection of the patella, and the LM, along with its type, was identified. The thickness, width, and length of the LM joint were measured in all the cadavers. The Structure of the LM was assessed using hematoxylin and eosin stains. Results: The study results showed that LM was seen in all the knees studied. Type I LM was predominant with a single band seen in 85% of cadavers. Type 2a and 2b were seen with double bands and triple bands respectively. Type 3 LM was seen as a vertical septum that divided the joint cavity into two compartments. The thickness of LM at the distal and proximal end was significantly higher on the left side and the length of the ligament was found to be 28.14±2.33mm. LM had rich vascularization and was comprised of dense connective tissue. Conclusion: The present study concludes that LM was initially considered an accidental finding. However, its presence is now being confirmed and is now considered an anatomical feature. Knowledge concerning LM is vital for the assessment of anterior knee pain with the detection of no definitive pathology.