Introduction: Urinary cytology has prominent role in the multidisciplinary diagnostic approach to bladder cancer. It is used as a valuable adjunct to cystoscopy and biopsy for diagnosis and follow up of patients with bladder cancer. Urine Cytological examination is a simple, safe, and inexpensive method to detect hidden urothelial tumours. Histopathological analyses will be used to confirm urine cytology. Based on this aim of our study is to Correlate Urine cytology with Histopathology of the Bladder Urothelial Cell Carcinoma therefore to Study the Role of Urinary Cytology in the diagnosis of Bladder Urothelial Cell Carcinoma and to find out the Correlation between the Grading by Urine cytology and Histopathology. Methodology: This study was done as a prospective clinical study done on 110 patients admitted in Department of Urology, Tirunelveli medical college in patients presented with hematuria and lower urinary tract symptoms due to bladder Urothelial cell carcinoma detected by ultrasonography or CT. Urine samples are typically taken three hours after the initial morning void. Cystoscopy was performed in all patients using rigid cystoscope and details of growth are noted. Material was obtained from TURBT biopsy, Radical Cystectomy specimen. Results: Coming to ultrasound findings single tumor was seen in 36 patients and multiple tumors in 74 patients. Tumor size was less than 2 cm in 14 patients, 2-5 cm in 20 patients and more than 5 cm in 76 patients. Tumor was low grade in 43 patients and high grade in 67 patients. Coming to tumor staging 30 patients had pTis, 10 had PTa, 28 had PT1 stage and rest 42 had PT2 staging. Coming to urine cytology in 52 patients it was positive, 14 patients it was suspicious, 13 patients it was atypical and in rest 31 it was negative. We next compared histological grade with urinary cytology and high grade has significant correlation with the positive urinary cytology. Further, we also correlated tumor staging with the urinary cytology and as staging increases more cases have positive urinary cytology. Conclusion: Urine cytology of the voided urine has both diagnostic and prognostic utility; a high-grade positive cytology is likely to identify patients at high risk for invasive and high-grade tumours. In order to diagnose low-grade cancers that voided Urine cytology largely missed; cystoscopy is crucial. Particularly for high-grade tumours, urinary cytology is still a useful technique for the identification and tracking of bladder UCC.