Original Articles
Endometrial Compaction Following Progesterone Supplementation in IVF Cycles: A comprehensive analysis | |
Dr. Shikha Sonker, Dr. Sweta Agrawal | |
Background: Embryo implantation is a complex and poorly understood process. The study was conducted to evaluate the effect of progesterone supplementation on endometrial compaction during an in vitro fertilization (IVF) cycle and its potential implications on embryo implantation and overall IVF outcomes. Material & methods: The present multi centric and retrospective study was carried out at Ashoka IVF care Bhopal and Raipur over a period of 5 year. All the patients coming for ivf who fulfilled inclusion criteria were included in the study. When the endometrial thickness reached ≥7 mm, usually around 10-12 days post estrogen the patient’s commenced injections of progesterone.Embryos were thawed and transferred on day 6 of progesterone. Data was recorded.Statistical Analysis was performed using SPSS version 23. Results: The baseline characteristics were compared and there was no statistical significance.There was no statistically significant difference between the two groups with regard to the type of fertility (p value = 0.377). The comparison showed statistically significant association between endometrial compaction status and pregnancy results (p value >0.005) in all three groups i.e. Endometrial Compaction, EndometrialThickness increased, Endometrial thickness unchanged. The comparison showed no statistically significant association between endometrial compaction status and pregnancy results in compaction group. Conclusion: EC may hold promise for the future as a non-invasive predictor of positive pregnancy outcomes. A large and well-designed clinical trial to rigorously assess endometrial compaction as a non-invasive predictor of a successful pregnancy is warranted. |
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