Background: Cardiovascular disease (CVD) continues to be a leading cause of death worldwide and contributes significantly to the disease burden in populations everywhere. The present study was conducted to assess knowledge of patients with cardiovascular disease. Materials & Methods: 180 CVDs patients were given a questionnaire. Oral health status, oral health care behaviors and attitudes, dental self-care confidence, oral health knowledge and beliefs, information obtained on oral health since a heart diagnosis, and social and family support were all included in the study questionnaire. Results: There were 95 males and 85 females. Cardiovascular condition was CAD in 45, arrhythmia in 36, hypertension in 74 and heart failure in 25. Marital status was married in 108 and unmarried in 72. The difference was significant (P< 0.05). Oral health status was excellent in 17%, very good in 10%, good in 40%, fair in 30% and poor in 3%. Oral health problems were dental caries in 15%, tooth ache in 32%, sensitivity in 23%, bleeding gums in 5%, dry mouth in 10% and loose teeth in 15%. Importance of oral health compared to overall health was low importance (0–4) in 9%, neutral (5) in 15% and important to extremely important (6–10) in 76%. They used to brush teeth/denture few times a week in 18%, once a day in 22%, 2 or more times a day in 54% and never in 6%. Oral hygiene products used were fluoride toothpaste in 82%, dental floss in 18%, mouthwash in 19% and sugar free chewing gum in 15%. Last dental visit<1yearwas seen in 74%, 1-2 years in 11% and >2 years in 15%. The difference was significant (P< 0.05). Conclusion: Low awareness of the significance of oral health and a high frequency of self-reported oral health issues were observed in individuals with CVD.