Original Articles
Correlation of APRI index with Child Pugh score in patients with liver cirrhosis | |
Dr.Yash Mishra, Dr.Devendra P.S. Rajput, Dr.Shobhik Bhardwaj, Dr.Rahul Govindani, Dr. Rishabh Patel, Dr.Diwakar Patel , Dr.Anubha Namdeo, Dr. Sumit Pattaiya, Dr. Avinash Jharia | |
Background: Liver Cirrhosis is defined as a diffuse process with fibrosis and nodule formation. The recent additions to the list are aspartate aminotransferase to-platelet ratio index (APRI) and gamma-glutamyltranspeptidase to platelet ratio index. Hence; the present study was conducted for assessing correlation of APRI index with Child Pugh score in patients with liver cirrhosis Materials & methods: An observational cross-sectional study was conducted at L.N. Medical College and Research Centre & J.K. Hospital, Bhopal, among 94 patients with liver cirrhosis. The study aimed to assess liver fibrosis using the APRI index and classify patients according to the WHO classification and Child-Pugh score. Data was analyzed statistically, and results were represented in tables, charts, and graphs. The study provides insights into the relationship between APRI scores, liver fibrosis, and Child-Pugh classification in patients with liver cirrhosis. Results:36.2% had an APRI index ≤1.49, 16.0% had an APRI index between 1.5-1.99 and 47.9% had an APRI index ≥2.8.5% had a Child Pugh score of 5-6, 45.7% had a score of 7-9 and 45.7% had a score of 10-15.Correlation of APRI index with Child Pugh score in patients with cirrhosis of liver results revealed significant correlations with a p value of 0.000 for APRI 2 and 0.014 for APRI 1.5-1.99. Conclusion: This study shows the significant correlation between the APRI index and Child-Pugh scores highlighting that higher APRI scores are indicative of more severe liver disease. The APRI index ease of calculation, relying solely on AST levels and platelet counts, makes it a practical and economical choice for assessing liver cirrhosis severity compared to the more complex Child-Pugh score, which require multiple variables and detailed clinical assessments. |
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