Introduction:Oral disease has detrimental effects on an individual’s physical and psychological wellbeing and it reduces quality of life. Oral health is not only important to person’s appearance and sense of well-being, but also to person’s overall health. Aim of the study: To assess the dental caries experience and its relationship with the oral health quality of life among 15-year-old school children. Material and methods:The present cross-sectional study was conducted to among 600 children aged 15 years of Patna, Bihar in which DMFT along with oral health related quality of life using Child Oral Health Impact Profile-SF 19 Questionnaire was recorded. The means and standard deviations of the measurements per group were used for statistical analysis (SPSS 22.00 for windows; SPSS inc, Chicago, USA)and the level of significance was set at p < 0.05. Results: The mean score among males it was 8.95±2.65 and among females it was 8.7±2.36. when the results were compared with gender it was found to not statistically significant with all domains. The relation of COHIP Score and its domain with DMFT showed statistically significant results. The Pearson correlation between COHIP with decayed, missing, filled and DMFT, there was negative correlation with Pearson correlation value r=-0.26 while for decayed, missing and overall DMFT it showed positive correlation. Conclusion:In present study, having dental caries which had negative effects on children’s oral health-related quality of life. The children’s self-reported COHIP reports associations between their oral health status and COHIP Domains especially for social and emotional well-being.