Background: Stroke is a leading cause of disability and death worldwide. The World Health Organization defines stroke as a rapid onset of focal or global cerebral dysfunction, lasting 24 hours or longer, with no apparent cause other than vascular origin. The brain's blood supply comes from four vessels, including the internal carotid arteries and vertebral arteries. Hence; the present study was conducted for assessing the prevalence of carotid and vertebral artery stenosis in acute stroke patients. Materials & methods:The cross sectional observational study was conducted in the Department of General Medicine, L.N. Medical College and J. K. Hospital, Kolar Road, Bhopal, M.P. 75 patients admitted to the hospital with acute stroke aged above 18 years and patient or attendant giving informed consent. The clinical profile of patients was evaluated. The radiological investigations were performed as per the guidelines. The following symptoms suggestive of Stroke were evaluated: Motor Weakness, Headache / Dizziness, Altered Sensorium, Memory, Speech, Cranial nerves, Sensory deficits, Visual disturbances,etc. If any of these symptoms were present, the duration of symptoms was noted. Carotid and vertebral artery stenosis was assessed by means of non-invasive ultrasonography of the carotid and vertebral arteries. High frequency linear probe (5-12 Hz) Ultrasonography combines gray scale ultrasound images with a Color Doppler ultrasound assessment of blood flow velocity. Results:Results categorizes subjects based on Doppler ultrasound findings into Normal study, Mild, Moderate, Severe and Complete stenosis. The frequency distribution of Doppler findings categorized by the vascular territory involved (MCA, ACA, and Posterior Circulation). It lists the number of cases for each Doppler finding type: Normal study, Mild, Moderate, Severe and Complete stenosis. The Chi-square value is 9.48 with a p-value of 0.661, indicating no significant association Conclusion: The study revealed that anterior circulation strokes were more common, accounting for 80% of cases, while middle cerebral artery territory was most vulnerable to vascular disease. The majority (53.3%) had normal Doppler findings and stenosis was observed in 46.7% cases, in which 30.3% cases had significant stenosis.