Background:Intussusception is a prevalent cause of intestinal obstruction in pediatric patients, requiring rapid identification and intervention to prevent bowel necrosis and potential loss of bowel segments. Non-operative management remains the preferred approach for treating intussusception. This study aimed to assess the presentation and management strategies of intussusception among cases presenting at a tertiary care center of southern Rajasthan. Materials and Methods: A retrospective study was conducted on cases of intussusception that underwent ultrasound-guided hydrostatic reduction at a tertiary care center of southern Rajasthan. A total of 123 cases were included in the analysis. Results:The average age of the participants was 15.5 ± 11.6 months, with a notable male predominance. The most frequently reported symptoms were abdominal pain (76.42%), vomiting (65.85%), abdominal distension (44.72%), blood in stools (34.96%), constipation (43.09%), and diarrhea (34.15%). All patients underwent ultrasound-guided hydrostatic reduction, with an overall success rate of 85.37%. The remaining cases required open manual reduction or resection-anastomosis procedures. The average hospital stay was 5.4 ± 2.9 days, and no mortalities were observed. Conclusion:Intussusception is more common in males, in children < 2 years, and presents with abdominal pain and vomiting. Ultrasound-guided hydrostatic reduction is an effective treatment for intussusception, demonstrating a high success rate and lower morbidity.