Background: Fine needle aspiration cytology (FNAC) is the primary, quick, less invasive procedure in diagnosing suspected and unsuspected primary and metastatic lymph nodes lesion. Aim: To categorise cytological aspirate from lymph node according to Sydney system and to evaluate the applicability of Sydney system. Methods: The study was done at Department of pathology, Karwar institute of medical sciences, Karwar from March 2023 to September 2023. Patient with clinical history of lymphadenopathy from any site were subjected to FNAC.Smears were fixed in alcohol and stained with H&E and Pap stain and examined under microscope. Results: Of 83 lymph node FNAC mean age was 40 years with male predominance. According toSydney System, lesions were classified as L1 Unsatisfactory-4 cases (4.9%), L2 Benign-64 cases (79%), of which Reactive lymphadenitis- 49 cases (76%), Necrotising lymphadenitis-2(3.1%), Suppurative lesions-10(15.6%), Granulomatous lesion -4(6.25%). L3AUS/ALUS-1 case (1.2%), L4 Suspicious -4 cases (4.8%), L5 Malignant-9 cases (10.8%). Conclusion The proposed 2020 Sydney system provides clear cut terminologies in producing reports and calculating risk of malignancy in each category and alerting the clinicians for further follow up.