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Volume 13 Issue 12 (December) 2024

Original Articles

Study Of Asymptomatic Bacteriuria And Its Obstetrics And Perinatal Outcomes After Treatment In Early Vs Late Pregnancy In Tertiary Care Hospital
Dr. Utkarsha Khajuria, Dr. Urvashi Sharma, Dr. Ankita Sharma

OBJECTIVES • To compare obstetric outcomes in women detected and treated for ASB in early pregnancy with those detected and treated late in pregnancy • To compare perinatal outcomes in women detected and treated for ASB in early pregnancy with those detected and treated late in pregnancy. MATERIAL & METHODOLOGY: This prospective observational cohort study was conducted at Shri Maharaja Gulab Singh Hospital, Jammu over a period of one year from 1st November 2019 to 31st October 2020. Group A comprised of 100 asymptomatic pregnant women till 20 weeks and group B comprised of 100 patients between 32-34 weeks. Midstream urine samples were obtained and were sent for culture and sensitivity. Women from both the groups having ASB on the basis of urine culture report were treated as per antibiotic sensitivity for 7 days. All patients were followed up in antenatal clinic till delivery and obstetric and perinatal outcomes were observed till 7 days. RESULTS: Comparing the maternal outcomes in both the groups PTL was 27% in group A and 10% in group B with odds ratio of 3.32 with p value=0.001. PROM occurred in 6% in group B whereas no case was seen in group A. Odds ratio is 12.77 and 95% CI lies between 0.69-230.5. PPROM occurred in 8% of cases in group B and no case in Group A with p-value= 0.008. Odds ratio is 17.3 with 95% CI ranging between 0.98-305.5. These were significantly associated whereas anemia in group A was 28% and 22% in group B with odds ratio of 1.37 with p value = 0.32, gestational HTN in group A and Group B are 16% and 10% respectively with 1.71 odds ratio with p value = 0.2 and pyrexia in group A is 3% and no case in group B had no significant association in both the groups. Comparing fetal outcomes in group A and Group B. IUGR in fetuses were found in 12% in group B whereas 4% in group A. Odds ratio is 3.27 with significant association with p value=0.03 and 95% CI lies between 1.012-10.52. LBW was found in 9% and 34% cases in groups A and B respectively with odds ratio of 5.2 and highly significant association. NICU admissions were significantly reduced. Around 10% were admitted in group A and 28% in group B with odds ratio of 3.5 with p value =0.0017 which was significantly associated. CONCLUSION: This study concluded that PTL, PROM and PPROM and FGR, LBW and NICU admissions were significantly reduced with early detection and treatment of ASB in pregnancy.

 
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