Original Articles
Comparison of different concentration of intra-tympanic methylprednisolone injections in subjective cochlear tinnitus | |
Dr. Vipul Kumar Chaudhary | |
Background: Most people believe that tinnitus results from an increase in the auditory neurons' spontaneous activity. Tinnitus can manifest with normal hearing, even though the majority of cases have hearing loss.The present study was conducted to compare different concentration of intra-tympanic methylprednisolone injections in subjective cochlear tinnitus. Materials & Methods: 60 patients with complaint of abnormal ringing in earswere divided into 3 groups of 20 each. Group I received 0.5ml of 40 mg/ml concentration methylprednisolone solution injected intratympanically, 125 mg/ml in group II and 250 mg/ml in group III. The groups were compared in terms of subjective tinnitus intensity and loudness matching after the intervention. Results: Group I had 11 males and 9 females, group II had 10 males and 10 females and group III had 8 males and 12 females. Group I showed improvement in 2, worsening in 2 and no change in 16, group II had improvement in 3, worsening in 1 and no change in 16 and group III had improvement in 3 and no change in 17 patients. The difference was non- significant (P> 0.05).4 patients each in group II and group III had cured and 3 patients in group I, 5 in group II and 6 in group III showed improvement. The difference was non- significant (P> 0.05). Conclusion: Subjective measurement of tinnitus intensity using a questionnaire revealed no discernible improvement in the three treatment groups in the current investigation. The loudness matching test for tinnitus also yielded a non-significant result. At different concentrations, the intratympanic methylprednisolone injection produced uneven and subpar results. |
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