Background: Anemia is characterized by a decrease in the circulating mass of red blood cells (RBCs) below established normal thresholds. The oral symptoms associated with stomatitis and glossitis due to nutritional deficiencies have been well-documented. Hence; the present study was undertaken for assessing the occurrence of oral mucosal lesions among patients of microcytic anemia. Materials & methods: This study design was cross-sectional and analytical study. After getting approval from Institutional Ethics Committee, this study was conducted in the Department of Medicine, Shyam Shah Medical College and associated Sanjay Gandhi and Gandhi Memorial Hospital, Rewa, Madhya Pradesh from September 2022 to August 2023 on 333 patients of orofacial diseases. All the patients were explained about the study and a written consent were obtained from each of them. The sample of venous blood is collected by venipuncture and sample was analyzed for haemoglobin, complete blood count, RBC indices. Statistical analysis was done for all the recorded data. After compilation and tabulation of data, appropriate statistical tests were applied. P-value< 0.05 was considered statistically significant. Results: On oral cavity examination, the most common findings was mucosal pallor found in 323 patients (97%). The next most common finding on tongue was atrophic glossitis in 107 patients (32.13%) .Other significant oral cavity findings comprised of fissured tongue in 103 patients(30.93%) and angular chelitis in 74 patients (22.22%) , geographic tongue in 33patients (9.91%) , oral ulcers in 67 patients (20.12%), candidal infection, lichen planus etc. Conclusion: Since the oral cavity has been called the mirror of the human body because many systemic diseases have relatively early oral manifestations, it is imperative that iron deficiency and associated anemia be examined in children.