Introduction: Pain and fatigue are common and debilitating symptoms experienced by many patients undergoing long-term dialysis. Renal providers face numerous challenges in managing these patients, including medication side effects, fluid overload, anemia, and cardiovascular complications. Aim: This study examines the effectiveness of intradialytic leg exercise in reducing pain and fatigue among hemodialysis patients at Dasmesh Hospital in Faridkot, Punjab. It also explores the relationship between pain, fatigue, socio-demographic factors, and the patients' hemodialysis treatment. Materials and methods: A pre-experimental study was conducted to assess the effectiveness of intradialytic leg exercise on pain and fatigue among patients undergoing hemodialysis The study was carried out at Dasmesh hospital in Faridkot Punjab, and a total of 60 participants were enrolled. The study subjects were selected using a purposive sampling technique. Data were collected using demographic profiles, numeric pain scale and fatigue scale throught structure interview schedule.After pretest intradialytic leg exercise were, performed t post-test was conducted after this. The IBM SPSS version 26 was used for data analysis and interpretation. Results: The study found . The pretest mean score of pain was 5.78 S.D 1.923, whereas the posttest mean score of pain was 5.13 S.D 1.722. The mean difference was 0.650. A paired ‘t’ test was applied to find out the statistical significance of the results. The results showed that t59=4.569, p=0.001, which indicates a high level of statistical significance at the 0.01 level. The pretest mean score of fatigue was 32.7 S.D was 9.062, whereas the posttest mean score of fatigue was 30.5 S.D was 8.926. The mean difference was 2.217. A paired ‘t’ test was applied to find out the statistical significance of the results. The results showed that t59=4.113, p=0.001, which indicates a high level of statistical significance at the 0.01 level. These finding indicated that intradialytic leg exerceses as effective .hence hypothesis H3 is accepted. Conclusion: In conclusion, this study emphasizes the positive impact of intradialytic leg exercise in reducing both pain and fatigue among patients undergoing hemodialysis. By incorporating this low-cost and feasible intervention into routine care, healthcare providers can improve the quality of life and well-being of patients with chronic kidney disease. These findings have important implications for the management of pain and fatigue in hemodialysis patients and highlight the need for further research in this area.