Background:The term "uterine and adnexal pathologies" describes a range of illnesses and disorders that can impact the female reproductive system's uterus and adnexal components. The present study was conducted to evaluate the role of diffusion-weighted imaging and MRI in identifying uterine and adnexal lesions. Materials & Methods:70 patients with uterine and adnexal lesions were selected. Siemens Avanto Magnetic Resonance Imaging (1.5 Tesla) was performed on each. Results: The age group 21-30 years had 26 patients, 31-40 years had 37 and 41-50 years had 7 patients. The difference was non- significant (P> 0.05). Benign lesions were 56 and malignant lesions were 14. Under benign, 49 were cystic, 5 were solid and 2 were solid-cystic. Under malignant, 7 were cystic, 3 were solid and 4 were solid-cystic. The difference was significant (P< 0.05). Diffusion restriction was absent in 23 benign uterine and cervical lesions and present in 8 malignant lesions. Diffusion restriction was absent in 18 and present in 15 benign adnexal lesions and present in 6 malignant lesions. The difference was significant (P< 0.05). The sensitivity, specificity, positive predictive, negative predictive value and accuracy of MRI in detecting and differentiating benign and malignant uterine and adnexal lesions was 95%, 100%, 100%, 97.2% and 96.4% respectively. Conclusion: Lesions in the uterus and adnexa can be easily identified and described using magnetic resonance imaging (MRI). DWI has a limited significance in cases of adnexal lesions because many benign lesions had low ADC values.