Introduction: Adhering to medication regimens is crucial for enhancing health outcomes in individuals with diabetes and related comorbid conditions. This study aimed to delve deeply into the factors influencing patient compliance within G2 clinics. Methods: This was an observational cross-sectional study conducted among outpatients at G2 Clinics from September 2022 to September 2023. Individuals aged between 10 and 80 years, diagnosed with diabetes mellitus (DM) attending G2 Clinics and currently undergoing treatment with oral hypoglycemic agents and/or insulin therapy were included.Structured interviews were conducted to assess patient compliance, focusing on key topics such as medication adherence, dosage consistency, lifestyle modifications, and barriers to compliance. Results: A total of 300 patients were included with mean age of 48.92 years.The majority of patients (64.3%) were in the age group of 31-60 years. Patients aged 61-80 years had comparatively higher medium compliance (56.2%) than other age groups.Medium compliance was observed among patients with diabetic diet (51.5%) whereas low compliance was observed among patients without diabetic diet (53.9%). Higher proportion of patients with duration of type 2 DM<5 years showed low compliance (75.6%). Conclusion: This study highlights the need for targeted interventions to improve medication adherence among younger patients.