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Volume 13 Issue 4 (April) 2024

Original Articles

Diagnostic utility of FNAC in breast lesions and its correlation with histopathology
Dr. Akhtar Un Nisa Salaria, Akshiptika, Dr. Subhash Bhardwaj

Background: Breast lumps are among the most frequent complaints that surgical oncology departments get, therefore it's critical to distinguish between benign and malignant disorders before beginning treatment. The present study was conducted to assess diagnostic utility of fine needle aspiration cytology in breast lesions. Materials & Methods: 215 cases of FNAC was conducted in the Department of Pathology at Government Medical College Jammu. Aspiration was done with 10 ml disposable syringe fitted with 21gauge needle and Franzens handle. Material spread on glass slides was wet fixed & stained with pap and Giemsa, occasionally keeping few unstained slides for later use. Histopathological correlation was available in 91 cases. The specimens were examined, representative tissue sampled and the sections were stained with H&E. Results: Out of 215 patients, males were 9 and females were 206. Out of 9 male patient lesions, 7 were benign and 2 were malignant. 7 cases of gynaecomastia mostly in 30 to 40 years, 2 cases of Duct cell Carcinoma at 58 years & at 65 years. The difference was significant (P< 0.05). Out of 206 smears in females, 13 were inadequate smears, out of 193 adequate smears, 171 smears were reported as neoplastic, out of which 127 were benign and 44 were malignant. 22 were reported as non- neoplastic. The difference was significant (P< 0.05). Common lesions in female patients was fibroadenoma 87, malignancy 44, phyllodes 4, fibrocystic disease 26, papilloma 3, acute mastitis 9, granulomatous mastitis 10, galactocoele 3, simple cyst7, and pagets 1. The difference was significant (P< 0.05). Common malignancies were medullary Ca. in 4, duct cell carcinoma- NOS in 37, pure mucinous Ca. in 1, Sq cell Ca in 1, and mixed mucinous Ca. in 1 case. The results showed sensitivity- 97.2 %, specificity- 83.4% , PPV- 88.2%, and NPV – 96%. Conclusion: Our study highlights the continuing role of fine needle aspiration cytology in the diagnosis of breast lesions & proves that it is an extremely accurate, well-tolerated, relatively non-invasive and low-risk test that obviates the need for surgical intervention in most benign conditions and disseminated malignancies.

 
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