Background:An open wound or sore that develops on a diabetic's foot is known as a diabetic foot ulcer. Diabetes-related problems such peripheral neuropathy (damage to the nerves) and poor circulation frequently lead to the development of these ulcers. The present study was conducted to assess the efficiency of the management of diabetic foot ulcers with PRP and conventional dressing. Materials & Methods:70 patients with diabetic foot ulcersof both genderswere divided into 2 groups of 35 each. Group I received homologousplatelet dressings, and group II patients receivedconventional moist wound dressings. A comparison was made between parameters such skin grafting, necrotic tissue, length of hospital stay, number of wound debridements, and wound dressing, among others. Results: There were 17 males and 18 females in group I and 19 males and 16 females in group II. The mean duration of hospital stay was 18.2 days in group I and 35.1 days in group II. The mean wound debridement days was 3.9 in group I and 17.5 in group II. The mean wound dressing days was 7.5 in group I and 41.2 in group II. The skin grafting was required in 7 patients in group I and 12 patients in group II. The difference was significant (P< 0.05). Conclusion: In terms of split skin grafting, length of hospital stay, number of wound debridements, and length of wound debridement, patients treated with platelet dressings outperformed those treated with traditional wound dressings.