Background: Hypertension is a significant cardiovascular risk factor with complex metabolic interactions. In the Indian population, the relationship between newly diagnosed hypertension and lipid metabolism remains incompletely understood, highlighting the need for comprehensive epidemiological research. Objectives: To investigate the lipid profile variations in newly diagnosed hypertensive patients across different demographic segments in India, and to assess the prevalence of dyslipidemia in this patient cohort. Methods: This prospective cross-sectional study recruited 500 patients with newly diagnosed hypertension from urban and rural healthcare centers. Participants underwent comprehensive lipid profile assessment, including total cholesterol, triglycerides, high-density lipoprotein (HDL), and low-density lipoprotein (LDL) measurements. Demographic data, anthropometric measurements, and blood pressure readings were simultaneously recorded. Results: Mean total cholesterol levels were significantly elevated in hypertensive patients compared to normotensive controls (p<0.001). Triglyceride levels showed a substantial correlation with systolic blood pressure (r=0.432, p<0.01). Approximately 68% of newly diagnosed hypertensive patients demonstrated abnormal lipid profiles, with higher prevalence in urban populations. Age, body mass index, and dietary patterns significantly influenced lipid metabolism. Conclusion: The study reveals a strong interrelationship between hypertension and lipid profile abnormalities in the Indian population. These findings underscore the importance of comprehensive metabolic screening and integrated management strategies for newly diagnosed hypertensive patients.