Background: Hemorrhoids are a common anorectal condition affecting a large proportion of the adult population. Rubber band ligation (RBL) is a widely accepted non-surgical treatment for second- and selected third-degree hemorrhoids. This study aimed to evaluate the efficacy, patient satisfaction, and post-procedural outcomes of RBL in patients with second- and third-degree hemorrhoids. Methods: A prospective clinical study was conducted on 78 patients diagnosed with second- (n=46) and third-degree (n=32) hemorrhoids. Demographic data, clinical presentation, duration of hospital stay, patient satisfaction scores, and post-procedural complications were recorded and analyzed. Statistical significance was assessed using appropriate tests. Results: The majority of patients were middle-aged males, with bleeding per rectum being the most common symptom. Patients with second-degree hemorrhoids had significantly shorter hospital stays (mean 1.23 days) compared to third-degree (mean 1.89 days, p<0.001). Satisfaction scores were higher in second-degree cases (median score 7 vs. 5, p<0.001). Most complications were minor and self-limiting. One-month follow-up revealed minimal residual symptoms, low recurrence, and comparable need for repeat banding in both groups. Conclusion: Rubber band ligation is a safe, effective, and minimally invasive treatment for second- and selected third-degree hemorrhoids. It offers high patient satisfaction, especially in second-degree cases, with minimal complications and losw recurrence rates.