Background:A variety of criteria, including cramps, muscle twitches, circumoral numbness, hand and foot paresthesias, laryngeal stridor, carpopedal spasm, and convulsions, are used to classify tetany. The present study was conducted to evaluate the cases of tetany in adults. Materials & Methods: 56 cases of tetany of both genders were included. Etiology and clinical features of tetany was recorded. Results: Out of 56 patients, 30 were males and 26 were females. Common causes were hypomagnesaemia in 3, anxiety hyperventilation in 17, idiopathic hyperparathyroidism in 8, acute pancreatitis in 5, Bartter’ syndrome in 4, and vitamin deficiency in 19 patients. The difference was significant (P< 0.05). Common symptoms were cramps in 41, laryngeal stridor in 32, carpopedal spasm in 36, circumoral numbness in 20, muscle twitching in 19 and paresthesia of hand and feet in 38 patients. The difference was significant (P< 0.05). Conclusion: Vitamin deficiencies, hypomagnesemia, anxiety, hyperventilation, idiopathic hyperparathyroidism, acute pancreatitis, and Bartter's syndrome were among the major causes of tetany.