Original Articles
Echocardiographic Assessment of Cardiac Function in Patients with Liver Cirrhosis: A Cross-Sectional Study | |
Dr. Manoj Aggarwal, Dr. Mayur Namadeorao Bhosale | |
Background: This study aimed to evaluate cardiac function in patients with liver cirrhosis using echocardiographic parameters to identify early signs of cirrhotic cardiomyopathy and related cardiovascular dysfunction.Materials and Methods: A cross-sectional study was conducted on 120 patients diagnosed with liver cirrhosis at a tertiary care hospital. Patients underwent transthoracic echocardiography (TTE) to assess left ventricular (LV) systolic and diastolic function, right ventricular (RV) function, pulmonary hypertension (PHT), and atrial remodeling. Laboratory investigations, including liver function tests, were also analyzed. Results: The study population had a mean age of 55.23 ± 9.45 years, with 70.00% males. Child-Pugh class B (40.00%) was the most common stage of cirrhosis. Elevated AST (80.42 ± 19.76 IU/L) and total bilirubin (2.14 ± 0.79 mg/dL) indicated liver dysfunction. Echocardiographic findings revealed preserved LV systolic function (EF = 57.84 ± 4.78%) but diastolic dysfunction with an E/A ratio of 1.18 ± 0.29 and E/e' ratio of 9.82 ± 2.76. Right ventricular function was mildly impaired (TAPSE = 16.92 ± 2.87 mm), and PASP was elevated (34.92 ± 9.54 mmHg), suggesting mild pulmonary hypertension. Atrial enlargement was observed with a left atrial volume index (LAVI) of 29.87 ± 5.65 mL/m² and right atrial size of 39.48 ± 5.14 mm.Conclusion: This study demonstrates that subclinical cardiac dysfunction is common in cirrhotic patients, with diastolic impairment, right ventricular dysfunction, mild pulmonary hypertension, and atrial remodeling. Although LV systolic function remained normal, early diastolic dysfunction was evident, highlighting the need for routine echocardiographic screening in cirrhotic patients. Identifying cardiac abnormalities early may help prevent further complications and improve patient management. |
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