Original Articles
An Interconnection of Biomarkers in Correlation to Body Mass Index (BMI) and Lipid Peroxidation In Type 2 Diabetes Mellitus Patients | |
Jeetam Singh Rajput, Amit Chaudhary, Rajesh Kumar Arya, Pawan Sood | |
Background: Body mass index (BMI) is a traditional measurement practice that divides a person’s weight by their height to find out whether they have a healthy range of weight. The objective of this study is to understand the relation between BMI and prevalence of diabetes mellitus, hypertension, and dyslipidemia. Material and Method: The distribution of Body Mass Index (BMI) among this cohort of patients was analyzed in relation to the presence or absence of hypertension and dyslipidemia. The improper secretion of insulin results in alterations in the metabolism of lipids, proteins, and carbohydrates. This condition is also characterized by hyperglycemia and is commonly referred to as diabetes mellitus (DM). Results: Excessive free radicals cause oxidative stress, weakening the body's antioxidant defense system. This can lead to diabetic disorders and an increase in malondialdehyde (MDA) production. In cells, the breakdown of polyunsaturated fatty acids is seen as a key indicator and result of oxidative stress. Conclusion: This study found that individuals with diabetes had a higher Body Mass Index (BMI) than those in a control group. There was also a strong link between glycated hemoglobin, cholesterol, and MDA levels. To prevent and manage complications in type 2 diabetes, it is crucial to keep MDA and body weight at normal levels. More extensive studies are needed to confirm these findings. |
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