Background: Menopausal symptoms, including hot flashes, mood disturbances, and sleep disorders, significantly impact women's quality of life. While hormonal therapy is effective, concerns about its safety have led to increased interest in non-hormonal alternatives. This study evaluates the efficacy of non-hormonal therapies in alleviating menopausal symptoms. Materials and Methods: A randomized controlled trial was conducted with 120 menopausal women aged 45–60 years, divided into three groups (n=40 each): Group A received cognitive behavioral therapy (CBT), Group B was administered phytoestrogens, and Group C served as the control (placebo). The intervention lasted for 12 weeks. Symptom severity was assessed using the Menopause Rating Scale (MRS) at baseline, six weeks, and post-intervention. Statistical analysis was performed using ANOVA and post-hoc tests, with significance set at p<0.05. Results: At baseline, mean MRS scores were comparable across groups (CBT: 18.5±2.3, Phytoestrogens: 19.1±2.6, Control: 18.9±2.4, p=0.78). After 12 weeks, Group A showed a significant reduction in MRS scores (9.2±1.8, p<0.001), followed by Group B (12.1±2.2, p<0.01). The control group exhibited minimal improvement (18.3±2.1, p=0.09). Improvements in sleep quality and mood were more pronounced in the CBT group, while phytoestrogens were more effective in reducing vasomotor symptoms. Conclusion: Non-hormonal therapies, particularly cognitive behavioral therapy and phytoestrogens, effectively alleviate menopausal symptoms. CBT demonstrated superior efficacy in improving mood and sleep, whereas phytoestrogens provided significant relief from hot flashes. These therapies offer promising alternatives for women unable or unwilling to use hormone therapy.