Objective: This study aimed to comprehensively examine the role of dietary habits and physical activity in the prevention of cardiovascular diseases. Methodology: A mixed-methods research approach was employed, integrating both qualitative and quantitative methodologies to ensure a holistic understanding of the relationship between diet, physical activity, and cardiovascular health. A cross-sectional study design was implemented, incorporating a systematic review of existing literature, survey-based data collection, and statistical analysis of health records. Participants aged 18 and above were included, with data collected through structured dietary recall questionnaires, physical activity logs, and medical records. Advanced statistical techniques, including regression modelling, correlation analysis, and meta-analysis, were utilized to evaluate the impact of various dietary patterns and exercise regimens on CVD risk reduction. Results: The findings of this study demonstrated a strong and statistically significant association between heart-healthy diets and a lower incidence of CVDs. The Mediterranean diet exhibited the most pronounced protective effect, reducing cardiovascular risk by 35%, followed closely by the DASH (Dietary Approaches to Stop Hypertension) diet at 30% and high-fiber intake at 28%. Conversely, the consumption of processed foods and refined sugars was found to elevate CVD risk by 25% and 20%, respectively, underscoring the detrimental effects of poor dietary choices. Physical activity was equally crucial in cardiovascular disease prevention, with individuals engaging in moderate-intensity exercise (150 minutes per week) experiencing a 25% reduction in risk, while those participating in high-intensity physical activity (>300 minutes per week) achieved a 40% risk reduction. Notably, the combined effect of a balanced diet and regular exercise resulted in the most substantial reduction in CVD risk (50%), reinforcing the necessity of an integrated lifestyle approach. Additional protective factors included smoking cessation (22% risk reduction) and effective stress management (18% risk reduction), highlighting the multifaceted nature of cardiovascular disease prevention. Conclusion: This study provided compelling evidence that dietary modifications and regular physical activity were fundamental pillars in the prevention of cardiovascular diseases. The findings emphasized the critical importance of adopting a holistic lifestyle approach that synergistically integrates heart-healthy nutrition with consistent physical exercise. Given the profound impact of these interventions on cardiovascular health, public health initiatives should prioritize the promotion of balanced dietary patterns and active lifestyles to mitigate the escalating global burden of CVDs. The insights derived from this study serve as a robust foundation for developing strategic, evidence-based policies aimed at fostering sustainable behavioural changes and enhancing population-wide cardiovascular health outcomes.