Aim: This prospective, randomized controlled study aimed to compare the efficacy and safety of spinal anesthesia (SA) versus general anesthesia (GA) in patients undergoing laparoscopic cholecystectomy (LC), with a focus on intraoperative hemodynamics, postoperative recovery, complication rates, and patient satisfaction. Materials and Methods: A total of 100 patients scheduled for elective LC were randomly assigned to either the SA group (n=50) or the GA group (n=50). The primary outcomes measured were hemodynamic stability (heart rate and blood pressure), the feasibility of completing the procedure under spinal anesthesia, and the incidence of intraoperative and postoperative complications. Secondary outcomes included pain levels, time to ambulation, length of hospital stay, and patient satisfaction, which were assessed using standardized scales. Results: The study demonstrated no significant differences in demographic characteristics between the two groups. Intraoperatively, the SA group exhibited lower mean arterial pressure and heart rate, and a higher need for vasopressor support compared to the GA group. Postoperatively, the SA group had a significantly shorter time to ambulation, reduced hospital stay, and better pain control, with fewer patients requiring rescue analgesia. However, the SA group had a higher incidence of bradycardia and shoulder pain, while the GA group reported more nausea and vomiting. Patient satisfaction scores were significantly higher in the SA group, indicating better overall comfort and recovery. Conclusion: Spinal anesthesia for laparoscopic cholecystectomy offers several advantages over general anesthesia, including faster recovery, reduced hospital stays, and improved patient satisfaction. However, it may be associated with certain hemodynamic challenges and a higher incidence of shoulder pain. The choice of anesthesia should be tailored to individual patient factors and the clinical setting.