Background: In developing nations, diabetes mellitus (DM) is a serious public health issue. Drug usage studies of antidiabetic medications are crucial for encouraging patients with DM to take their medications sensibly and for providing the medical staff with useful information. Aims & Objective: To determine trends in the prescription of antidiabetic medications for people with type 2 diabetes.Materials and Methods: Social, demographic, and clinical factors as well as medication use were assessed in patients with established type 2 diabetes who visited the endocrinology outpatient clinic. Prescriptions for antidiabetic medications written for 1185 established T2DM patients during a two-month period were analyzed from the pharmacy databases of five general family clinics. Six kinds of antidiabetic medications were evaluated in the study: glitazones, α-glucosidase inhibitors, biguanides, sulfonylureas, insulin, and dipeptidyl peptidase-4 (DPP-4) inhibitors. Results: The majority of patients (41.6%) were prescribed metformine, followed by glimipride (25.3%), glipizide (8%), glibenclamide (10.6%), insulins (9.04%), voblibose (6.3%), and pioglitazone (5.7%). In the overall utilization pattern, about 22.7% of the patients were receiving monotherapy.Conclusion: The recommended medication is metformin, and the most popular combination with it is glibenclamide. Insulin as a monotherapy was not favored. The postprandial glucose levels were out of range despite combination treatment, which may indicate either poor patient compliance or improper therapy or insufficient dose. These individuals may benefit from the services of a clinical pharmacist in addition to medications.