Background: The pervasive use of mobile phones has raised concerns about the cognitive effects of electromagnetic radiation (EMR) exposure, particularly on visuomotor coordination and processing speed. Aim: This study aimed to assess the impact of prolonged mobile phone use on visuomotor coordination and processing speed. Methods and Material: The study was conducted using a cross-sectional design.Twenty healthy right-handed males aged 18–40 years were divided into two groups based on daily mobile phone call duration: Group I (≥1 hour) and Group II (<1 hour). Participants completed the Single Letter Cancellation Task (SLCT), Six Letter Cancellation Task (SxLCT), and Perceptual Speed Test (PST) to assess cognitive performance. Statistical Analysis and Results: Scores were analyzed using paired t-tests, and p < 0.05 was considered statistically significant. Group II performed significantly better than Group I in the SxLCT (p = 0.02), with a higher mean number of correct responses. Although Group II outperformed Group I in the SLCT and PST, the differences were not statistically significant (p > 0.05). Conclusions: Prolonged mobile phone use is associated with reduced visuomotor coordination, as evidenced by diminished performance in tasks requiring visual and motor integration. These findings underscore the cognitive risks of excessive mobile phone exposure and highlight the need for further research on its long-term effects.