Abstract Issue

Volume 14 Issue 1 (January) 2025

Original Articles

Association of metabolic syndrome and serum uric acid
Dr. Avinash Jhariya, Dr. Ashutosh Kumar, Dr. DP Singh, Sumit Pattaya, Rahul Govindani, Rishabh Patel, Shobhik Bhardwaj, Yash Mishra

Background: Metabolic syndrome, elevated concentrations of uric acid are associated with a variety of cardiovascular conditions. However, the association of uric acid and Metabolic syndrome remains controversial and limited experience exists on this relationship. Given the high prevalence of Metabolic syndrome in Indian population, in the present study we evaluated the association of serum uric acid levels and Metabolic syndrome components in the present study. Materials & methods: 273 patients fulfilling IDF Criteria for metabolic syndrome reporting at L.N. Medical College & J. K. Hospital, Kolar Road, Bhopal and satisfied the criteria inclusion criteria were selected for the study. Relevant clinical data was recorded in a structured proforma.Participants consented by endorsing a written consent form before samples were collected.The clinical profile of patients was evaluated as per the proforma.Data was analysed statistically. Analysis was done in the form of percentages, proportions and represented as tables, charts, graphs wherever necessary. Appropriate tests of significance were applied with p<0.05. Results: The study examined the distribution of 273 subjects across various age groups, finding that the majority (30.4%) fell into the 41-50 years category, followed by the 51-60 years group (27.1%). The study population was predominantly middle-aged and elderly, with a relatively balanced gender distribution (42.85% male, 57.14% female).Uric acid levels varied across age groups, with no clear pattern. Males had slightly higher uric acid levels than females, but the difference was not statistically significant. No significant correlations were found between uric acid levels and HDL cholesterol, waist circumference, or fasting blood sugar. Conclusion: In conclusion, this study demonstrates a significant association between metabolic syndrome and serum uric acid levels in middle-aged and elderly individuals. Elevated uric acid levels were found to be positively correlated with increased systolic and diastolic blood pressure, triglycerides, and smoking habits, suggesting a potential link between uric acid and cardiovascular risk factors.

 
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