Background: Pregnancy-related hypertensive disorders are one of the three lethal triads that contribute to maternal morbidity and mortality, along with infection and bleeding. Serum homocysteine levels can be measured to predict preeclampsia and prevent its consequences, such as eclampsia and placental disruption. This study aims to determine the correlation between blood homocysteine levels in a typical pregnancy and a pregnancy complicated by abruption and eclampsia.Methods: This prospective study was conducted over the course of a year, from October 2022 to September 2023, in prenatal patients with eclampsia, abruption, and normal pregnancies who were attending the Department of OBG, Coimbatore Medical College and Hospital.Results: Eclampsia is prevalent in primigravida in our study. CVT was frequently observed in 20% of cases of eclampsia. There was no discernible link between abruptio placenta and serum homocysteine levels, which are markers of the severity of eclampsia.Conclusion: Hyperhomocysteinemia is a predictor of eclampsia, according to this study. As a result, estimating serum homocysteine levels can be a standard part of prenatal care management at all hospitals.