Background: Overuse and misuse of antibiotics in hospitals contribute to the global issue of antimicrobial resistance (AMR). Antimicrobial stewardship programs (ASPs) aim to optimize antimicrobial use, improving clinical outcomes and minimizing resistance. This study evaluates the effectiveness of a "High-End Antibiotic Restriction Form" intervention in a tertiary care hospital to reduce overuse of selected broad-spectrum antimicrobials. Methodology: The study was conducted in the ICU of NIMS Medical College and Hospital. From September 2022 to February 2023, ICU admissions were reviewed. On November 20, 2022, a restriction form requiring justification for the use of high-end antibiotics (e.g., meropenem, vancomycin, teicoplanin) was introduced. Antibiotic consumption before and after the intervention was compared. Results: Thirty-four ICU admissions were reviewed. The restriction form was present in all cases, with 88% correctly filled out. Documentation of reconciliation and justification was 100%. No cases involved the use of more than three antibiotics concurrently. Post-intervention, significant reductions in high-end antibiotic consumption were observed. Conclusion: The "High-End Antibiotic Restriction Form" effectively reduced broad-spectrum antibiotic use in the ICU. This simple intervention ensured proper documentation and contributed to more rational prescribing, aiding in the fight against antimicrobial resistance. Further studies are needed to assess its long-term impact on clinical outcomes and resistance patterns.