Original Articles
A Comparative Study of Topical Phenytoin with Conventional Dressing versus only Conventional (5% Povidone Iodine) Dressing in the Management of Diabetic Ulcer | |
Dr. Pradeep Singhal, Dr. Ajay Kumar, Dr. Vinaysheel Singh Bisen, Dr. Maj. Anurag Bijalwan, Dr. Upamanyu Joshi | |
Aim/Introduction: This study is being done to see if Topical Phenytoin with Conventional (5% Povidone Iodine) Dressing acts as a better dressing modality in the treatment of Diabetic Ulcer and helps patient recover better than the Conventional (5 % Povidone Iodine) Dressing. Patients and Methods: A“Randomized Control Trial Study was conducted for a period of 18 Months. Total 60 patients with Diabetic Foot Ulcers were included in the study. The wounds were thoroughly debrided - surgically under anesthesia and ulcer dimensions (measuring maximum length and breadth using a sterile scale) were assessed immediately after debridement and were then reassessed after 7 days and 14 days in either type of dressings and compared. Results: Mean age of the study group was 56.53+12.02 and 76.7% patients had BMI>25 and mean BMI was 28.60 SD 3.95. 81.7 % of the patients had HbA1c > 7.5 and Mean HbA1c level was 9.20 SD 1.82. 45% of the patients had no comorbidities other than Type 2 Diabetes Mellitus whereas 31.7% of the patients had single comorbidity amongst which Hypertension was the most prevalent of all i.e. 41.7%. Mean Percentage of Granulation Tissue formed in 14 days in the Conventional Povidone Dressing Group was 50.83 SD 10.54 % whereas in the Topical Phenytoin with conventional dressing group is 69 SD 9.51 % which is significantly higher than the Conventional Povidone Iodine Dressing Group. (p value- <0.001). In Dressing done with Povidone Iodine, ulcers show 24.57 SD 4.91 % reduction in dimensions, whereas in Dressing done with Topical Phenytoin with Conventional dressing, ulcer show 37.07 SD 4.85% reduction in dimensions which is significantly higher (p value <0.001) than the Povidone iodine group. Conclusion: Topical Phenytoin with Conventional (5% Povidone Iodine) dressing, when used as a dressing agent for diabetic ulcers, performed better than conventional 5% Povidone Iodine Dressing in terms of Granulation tissue formation and reducing the ulcer dimensions. |
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