Background: Liver cirrhosis is associated with cardiac abnormalities, including QTc interval prolongation, which may predict cardiac involvement and poor outcomes.Objective: To analyze the correlation between QTc interval and liver function parameters (direct, indirect, and total bilirubin) in liver cirrhosis patients.Methods: This observational, cross-sectional study included 92 liver cirrhosis patients admitted to L.N. Medical College and Research Centre & J.K. Hospital, Bhopal. Patients with previous heart disease and those under 18 years old were excluded. Clinical, biochemical, and radiological evaluations were performed.Results: Significant increases in total bilirubin, direct bilirubin, and indirect bilirubin levels were observed with progressing disease severity (Child-Pugh scores A to C). Mean QTc interval values differed significantly among Child-Pugh score grades (p < 0.01). Higher bilirubin levels (total, direct, and indirect) were associated with QTc interval prolongation (>460 ms) (p < 0.01).Conclusion: This study demonstrates a significant correlation between QTc interval prolongation and liver dysfunction (reflected by elevated bilirubin levels) in liver cirrhosis patients. These findings support the utility of QTc interval as a potential marker for cardiac involvement in liver cirrhosis.