Background:The surgical treatment of diaphyseal forearm fracture-non-unions remains a therapeutic challenge for orthopaedic trauma surgeons. Masquelet technique, which is the use of a temporary cement spacer followed by staged bone grafting, is a recent treatment strategy to manage a posttraumatic bone defect. Hence; the present study was conducted for assessing the outcome of management of fracture non-union by Masquelet technique using external or internal fixator. Materials & methods:A total of 20 cases of infected forearm non-unions where the defects post-debridement ranged from 4 to 7.5 cm were enrolled. Complete demographic and clinical details of all the patients was obtained. All the patients were treated withMasquelet technique and follow-up was carried at 6 weeks,3 months, 6 months and 1 year. Pre-treatment biochemical and hematological findings were evaluated. Pre-treatment preparation was done. The antibiotic was continued for 6 weeks. All the results were recorded in Microsoft excel sheet and were subjected to statistical analysis using SPSS software.Results:Mean age of the patients were 43.9 years with majority proportion of patients were males. Right side involvement occurred in 13 cases and left in 7 patients. Four of them received internal fixation and 16 received external fixation. At the final follow-up, there was an improvement in the range of motion in all instances, with the wrist flexion ranging from 40° to 60° and the wrist extension ranging from 45° to 60°. The pronation range varied between 50° and 85°, whereas the pronation itself ranged from 60° to 85°. Recurrent infection was seen in one patient and joint stiffness was seen in 2 patients. Conclusion:Fracture non-union cases can be effectively managed by Masquelet technique using using external or internal fixator for stabilizing the affected area.